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KMID : 1225720150070010003
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Allergy, Asthma & Immunology Research : AAIR
2015 Volume.7 No. 1 p.3 ~ p.13
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Clinical Application of Exhaled Nitric Oxide Measurements in a Korean Population
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Song Woo-Jung
Kwon Ji-Won
Kim Eun-Jin
Lee Sang-Min
Kim Sae-Hoon
Lee So-Yeon
Kim Sang-Heon
Park Heung-Woo
Chang Yoon-Seok
Kim Woo-Kyung
Shim Jung-Yeon
Seo Ju-Hee
Kim Byoung-Ju
Kim Hyo-Bin
Song Dae-Jin
Jang Gwang-Cheon
Jang An-Soo
Park Jung-Tak
Yoon Ho-Joo
Lee Joo-Shil
Cho Sang-Heon
Hong Soo-Jong
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Abstract
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Nitric oxide (NO) is a biologic mediator of various physiologic functions. Recent evidence suggests the clinical utility of fractional exhaled NO (FeNO) as a biomarker for assessing asthma and other respiratory diseases. FeNO methodologies have been recently standardized by international research groups and subsequently validated in several Korean population studies. Normal ranges for FeNO have been reported for various ethnic groups, and the clinical utility has been widely evaluated in asthma and various respiratory diseases. Based on current evidence including most of Korean population data, this position paper aims to introduce the methodological considerations, and provide the guidance for the proper clinical application of FeNO measurements in Korean populations.
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KEYWORD
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Exhaled nitric oxide, reference value, guideline, position paper, asthma.
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